Grant proposal titled
Dynamic Quantum Crystallography for accurate structures, entropy and other thermodynamic properties for molecular crystals
by Anna Hoser
get funding from National Science Centre!
Congratulations!
In memory of Professor Robert H. Grubbs
‘We are stronger together than we are alone.’ New publication as a result of long-term and fruitful cooperation between Wozniak’s and Grela’s groups.
Ruthenium Olefin Metathesis Catalysts Bearing a Macrocyclic N-Heterocyclic Carbene Ligand: Improved Stability and Activity
Wioletta Kośnik, Dawid Lichosyt, Marcin Śnieżek, Angelika Janaszkiewicz, Krzysztof Woźniak, Maura Malińska, Bartosz Trzaskowski, Anna Kajetanowicz, Karol Grela
We’re hiring! (Sonata Bis 11)
SONATA BIS 11 grant awarded to dr Maura Malińska by National Science Centre, Poland.
Project title: True Bioisosteres – Structural and Thermodynamic Classification of Molecular Fragments for Ligand Design
We are looking for:
- Post Doc
- Technitian (PL, ENG)
- PhD Student
- MSc Students
- BSC Students
Cover Story
First Experimental Quantitative Charge Density Studies of Vitamin D Intermediate
Vitamins D are a group of fat-soluble secosteroids which play a regulatory role in the functioning of most cells. Rational design of new vitamin D analogs of increased therapeutic potency and lowered calcemic side effects requires high-resolution initial structures and a deep understanding of interactions with the vitamin D receptor. In this paper, using quantum crystallography methods, we present the first determination of the experimental quantitative charge density of an advanced intermediate of vitamin D analogues as well as a reconstruction of the theoretical electron density of final vitamin D analogues. Application of these methods allows for topological and electrostatic interaction energy analysis which is important for understanding biological effects.
Maura Malińska was awarded SONATA BIS
Congratulations!
We are excited to announce that Maura Malińska was awarded SONATA BIS grant entitled “True Bioisosteres – Structural and Thermodynamic Classification of Molecular Fragments for Ligand Design” by Polish National Science Centre. “
